Article View/Open
(1359)
Publication Export
| Citation Infomation |
| 社群 sharing |
Related Publications in TAIR
- > Simple Record
- > Full Record
| Field | Value |
|---|---|
| Title: | Accelerated Short-TE 3D Proton Echo-Planar Spectroscopic Imaging using 2D-SENSE with a 32-Channel Array Coil |
| Authors: | Otazo, Ricardo ; Tsai, Shang-Yueh ; Lin, Fa-Hsuan ; Posse, Stefan 蔡尚岳 |
| Contributors: | 應物所 |
| Keywords: | echo-planar spectroscopic imaging;parallel imaging;SENSE;regularization;large array coil |
| Date: | 2007.12 |
| Issue Date: | 2014-04-10 11:16:56 (UTC+8) |
| Abstract: | MR spectroscopic imaging (MRSI) with whole brain coverage in clinically feasible acquisition times still remains a major challenge. A combination of MRSI with parallel imaging has shown promise to reduce the long encoding times and 2D acceleration with a large array coil is expected to provide high acceleration capability. In this work a very high-speed method for 3D-MRSI based on the combination of proton echo planar spectroscopic imaging (PEPSI) with regularized 2D-SENSE reconstruction is developed. Regularization was performed by constraining the singular value decomposition of the encoding matrix to reduce the effect of low-value and overlapped coil sensitivities. The effects of spectral heterogeneity and discontinuities in coil sensitivity across the spectroscopic voxels were minimized by unaliasing the point spread function. As a result the contamination from extracranial lipids was reduced 1.6-fold on average compared to standard SENSE. We show that the acquisition of short-TE (15 ms) 3D-PEPSI at 3 T with a 32 × 32 × 8 spatial matrix using a 32-channel array coil can be accelerated 8-fold (R = 4 × 2) along y-z to achieve a minimum acquisition time of 1 min. Maps of the concentrations of N-acetyl-aspartate, creatine, choline, and glutamate were obtained with moderate reduction in spatial-spectral quality. The short acquisition time makes the method suitable for volumetric metabolite mapping in clinical studies. Magn Reson Med, 2007. © 2007 Wiley-Liss, Inc. |
| Relation: | Magnetic Resonance in Medicine,58(6), 1107-1116 |
| Data Type: | article |
| DOI: | http://dx.doi.org/10.1002/mrm.21426 |
| DCField | Value | Language |
|---|---|---|
| dc.contributor (Contributor) | 應物所 | en_US |
| dc.creator (Authors) | Otazo, Ricardo ; Tsai, Shang-Yueh ; Lin, Fa-Hsuan ; Posse, Stefan | en_US |
| dc.creator (Authors) | 蔡尚岳 | zh_TW |
| dc.date (Date) | 2007.12 | en_US |
| dc.date.accessioned | 2014-04-10 11:16:56 (UTC+8) | - |
| dc.date.available | 2014-04-10 11:16:56 (UTC+8) | - |
| dc.date.issued (Issue Date) | 2014-04-10 11:16:56 (UTC+8) | - |
| dc.identifier.uri (URI) | http://nccur.lib.nccu.edu.tw/handle/140.119/65243 | - |
| dc.description.abstract (Abstract) | MR spectroscopic imaging (MRSI) with whole brain coverage in clinically feasible acquisition times still remains a major challenge. A combination of MRSI with parallel imaging has shown promise to reduce the long encoding times and 2D acceleration with a large array coil is expected to provide high acceleration capability. In this work a very high-speed method for 3D-MRSI based on the combination of proton echo planar spectroscopic imaging (PEPSI) with regularized 2D-SENSE reconstruction is developed. Regularization was performed by constraining the singular value decomposition of the encoding matrix to reduce the effect of low-value and overlapped coil sensitivities. The effects of spectral heterogeneity and discontinuities in coil sensitivity across the spectroscopic voxels were minimized by unaliasing the point spread function. As a result the contamination from extracranial lipids was reduced 1.6-fold on average compared to standard SENSE. We show that the acquisition of short-TE (15 ms) 3D-PEPSI at 3 T with a 32 × 32 × 8 spatial matrix using a 32-channel array coil can be accelerated 8-fold (R = 4 × 2) along y-z to achieve a minimum acquisition time of 1 min. Maps of the concentrations of N-acetyl-aspartate, creatine, choline, and glutamate were obtained with moderate reduction in spatial-spectral quality. The short acquisition time makes the method suitable for volumetric metabolite mapping in clinical studies. Magn Reson Med, 2007. © 2007 Wiley-Liss, Inc. | en_US |
| dc.format.extent | 814881 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | - |
| dc.relation (Relation) | Magnetic Resonance in Medicine,58(6), 1107-1116 | en_US |
| dc.subject (Keywords) | echo-planar spectroscopic imaging;parallel imaging;SENSE;regularization;large array coil | en_US |
| dc.title (Title) | Accelerated Short-TE 3D Proton Echo-Planar Spectroscopic Imaging using 2D-SENSE with a 32-Channel Array Coil | en_US |
| dc.type (Data Type) | article | en |
| dc.identifier.doi (DOI) | 10.1002/mrm.21426 | en_US |
| dc.doi.uri | http://dx.doi.org/10.1002/mrm.21426 | en_US |
NO.64,Sec.2,ZhiNan Rd.,Wenshan District,Taipei City 11605,Taiwan (R.O.C.)
11605 臺北市文山區指南路二段64號 Tel：+886-2-2939-3091
© 2016 National ChengChi University All Rights Reserved.
DSpace Software Copyright © 2002-2004 MIT & Hewlett-Packard / Enhanced by NTU Library IR team Copyright © 2006-2017 - 問題回報 Problem return